Gel Filtration Chromatography allows biomolecule separation depending on its size and with no significant dilution. Smaller molecules pass significantly slower through the column than medium molecules. And large molecules are totally excluded. So larger molecules leave the column first followed by medium and smaller ones in the order of their decreasing size. Sepadextran is a beaded gel filtration medium prepared by cross-linking dextran and it is supplied in its dry form. ABT offers two types of Sepadextran (Sepadextran-25 & Sepadextran-50) that differ in their degree of cross-linking and hence in their degree of swelling and molecular fractionation range. Both types are available in three different particles sizes (Medium, Fine & Superfine).